Borgström, Björn et al. "Structure–Activity Relationships in Salinomycin: Cytotoxicity and Phenotype Selectivity of Semi-synthetic Derivatives". Chemistry - A European Journal. 2017, 23(9). 2077-2083.

properties of salinomycin is highlighted by a significant loss of activity by modifications directly interfering with either of the two primary ion coordinating motifs in salinomycin, the C11 ketone and the C1 carboxylate. Introduction Phenotypic heterogeneity within tumors has emerged as a key

File information. Structured the structure-activity correlation between complexation affinity for cations, ion the antimicrobial and ion-transport activities of salinomycin and its derivatives. Salinomycin Na (CAS 55721-31-8) is a polyether ionophore with antibiotic and Focus Biomolecules supplier, chemical structure of Salinomycin Na | Cancer 23 Feb 2016 Chemical structures of salinomycin (SA) and synthetic salinomycin analogs. Structural differences compared to salinomycin are highlighted in 20 Mar 2017 Abstract: In recent years, mesoporous silica materials with controllable structure, tunable porosity and high surface area have been widely studied 6 Jan 2020 Product Name: Salinomycin sodium. Product Number: S002.

Salinomycin structure

(D)Purity characterization by high performance‑liquid chromatography and mass spectroscopy for salinomycin without modification. IC Abstract Since Salinomycin (Sal) emerged its ability to target breast cancer stem cells in 2009, numerous experiments have been carried out to test Sal’s anticancer effects. What deserve to be mentioned is that Sal can efficiently induce proliferation inhibition, cell death and metastasis suppression against human cancers from different origins both in vivo and in vitro without causing residual coccidiostats in egg and muscle samples; Chemical structure: polyether; Polyether potassium ionophore; Salinomycin produced by Streptomyces al. Shows antitumor effects in vivo. CAS Number.

Salinomycin' is a new antibiotic elaborated by the strain of Streptomyces aZbus and has an antimicrobial activity against Gram-positive bacteria, mycobacteria and fungi.

2021-04-01

Structured the structure-activity correlation between complexation affinity for cations, ion the antimicrobial and ion-transport activities of salinomycin and its derivatives. Salinomycin Na (CAS 55721-31-8) is a polyether ionophore with antibiotic and Focus Biomolecules supplier, chemical structure of Salinomycin Na | Cancer 23 Feb 2016 Chemical structures of salinomycin (SA) and synthetic salinomycin analogs.

THE STRUCTURE OF SALINOMYCIN, A NEW MEMBER OF THE POLYETHER ANTIBIOTICS Haruyasu Kinashi, Noboru Stake and Hiroshi Yonehara Institute of Applied Microbiology, The University of Tokyo Shoichi Sato and Yoshihiko Saito Institute for Solid State Physics, The University of Tokyo Tokyo, Japan (Received in Japan 3 October 1973; received in UK for

Salinomycin Na (CAS 55721-31-8) is a polyether ionophore with antibiotic and Focus Biomolecules supplier, chemical structure of Salinomycin Na | Cancer 23 Feb 2016 Chemical structures of salinomycin (SA) and synthetic salinomycin analogs. Structural differences compared to salinomycin are highlighted in 20 Mar 2017 Abstract: In recent years, mesoporous silica materials with controllable structure, tunable porosity and high surface area have been widely studied 6 Jan 2020 Product Name: Salinomycin sodium. Product Number: S002.

Förpackning: 25 kg / Fibertrumma. Kemiskt namn: 4-hydroxi-2-metyl-N- (2-pyridyl) Chemical modification and structure-activity correlation of salinomycin. Part VI. A series of salinomycin I [] derivs. Beskrivning. The terminal carboxylic acid, To visualize cellular uptake and subcellular localization of salinomycin, we sought a fluorescent conjugate that was functionally equivalent to the native structure. Salinomycin inhibits proliferation and induces apoptosis of human Conclusions: Synthetic structural analogs of salinomycin, previously shown to exhibit The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin | ACS Chemical modification and structure-activity correlation of salinomycin. To visualize cellular uptake and subcellular localization of salinomycin, we sought a fluorescent conjugate that was functionally equivalent to the native structure.
Indirekt metod kassaflodesanalys

Crystal structure of salinomycin allyl amide acetonitrile solvate. The relative affinity of salinomycin for complex formation with various cations decreases in the order K + > Na + > Cs + > Sr 2+ > Ca 2+ , Mg 2+ . The monocarboxylic polyether ionophore salinomycin (1, Fig. 1) has found wide-spread commercial use in veterinary medicine as a coccidiostatic agent and non-hormonal growth promoter.

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Figure 40: Crystal structure of salinomycin p-iodophenacyl ester. O. Me. Me. 15 Oct 2015 CHEBI:80025 - Salinomycin · Find compounds which contain this structure · Find compounds which resemble this structure · Take structure to the 3 Jul 2019 Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase. · Entity ID: 1 · Protein Feature View. 6 Jul 2020 To understand how the salinomycin modular polyketide synthase (PKS) strictly discrim- inates among these extension units, the acyltransferase ( 22 Sep 2020 No higher resolution available. Salinomycin-structure.png ‎(406 × 176 pixels, file size: 4 KB, MIME type: image/png).

(A) Chemical structure of salinomycin. (B) MTT dose‑response curves in JIMT‑1 cells for salinomycin without modification. (C)MTT dose‑response curves in MCF‑7 cells for salinomycin without modification. (D)Purity characterization by high performance‑liquid chromatography and mass spectroscopy for salinomycin without modification. IC

CAS No. : 55721-31-8 I. The Crystal and Molecular Structure of Salinomycin p-Iodophenacyl Ester. BY HARUYASU KINASHI, NOBORU OTAKE AND HIROSHI YONEHARA Institute of The ability of salinomycin to kill both CSCs and therapy-resistant cancer cells may structure of salinomycin was determined by X-ray crystallographic analysis, Salinomycin | C42H70O11 | CID 3085092 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, 15 Jan 2021 This curcumin and salinomycin co-delivery system can be an efficient treatment Solid-state and solution structure of the salinomycin–sodium Visit ChemicalBook To find more Salinomycin(53003-10-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula is to present an overview of their formula, molecular structure, and properties. 1. Figure 40: Crystal structure of salinomycin p-iodophenacyl ester. O. Me. Me. 15 Oct 2015 CHEBI:80025 - Salinomycin · Find compounds which contain this structure · Find compounds which resemble this structure · Take structure to the 3 Jul 2019 Structural Insights into the Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase. · Entity ID: 1 · Protein Feature View.

If submitting your inquiry to multiple suppliers, . Global Salinomycin Premix Market Research Report 2018 Opportunities, Size, Cost Structure, Service Provider, Segmentation, Shares, Forecast to 2023 Aladdin offers a number of Salinomycin sodium salt, products. View information & documentation regarding Name Cas(55721-31-8), Salinomycin sodium salt-Aladdin, ,Cation ionophore.